Certain antibiotics can cause direct damage to the kidneys, especially if they are used in high doses or for an extended period. This type of kidney damage is known as nephrotoxicity. Some antibiotics, such as aminoglycosides (e.g., gentamicin, amikacin), vancomycin, and certain cephalosporins, are well-known culprits of nephrotoxicity.
Nephrotoxicity can manifest as acute kidney injury (sudden loss of kidney function) or chronic kidney disease (gradual loss of kidney function over time). Symptoms of kidney damage may include decreased urine output, swelling, fatigue, nausea, vomiting, and changes in urination patterns.
It's crucial to use antibiotics judiciously and under the guidance of a healthcare professional to minimize the risk of kidney damage. Patients with pre-existing kidney disease or those taking other nephrotoxic medications should be particularly cautious when using antibiotics and may require dose adjustments or alternative treatments. If you experience any concerning symptoms while taking antibiotics, it's essential to contact your healthcare provider promptly.
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